Innate Immune Pathway Modulator Screen Identifies STING Pathway Activation as a Strategy to Inhibit Multiple Families of Arbo and Respiratory Viruses

Investigators observed that Toll-like receptor 3 (TLR3), stimulator of interferon genes (STING), TLR8, and Dectin-1 ligands inhibited arboviruses, Chikungunya virus, West Nile virus, and Zika virus to varying degrees.