Osteoprogenitor-GMP Crosstalk Underpins Solid Tumor-Induced Systemic Immunosuppression and Persists after Tumor Removal

Scientists characterized breast and lung cancer-induced bone marrow ecosystem shifts pre- and post-tumor removal. Remote tumors progressively led to osteoprogenitor expansion, hematopoietic stem cell dislocation, and CD41− granulocyte-monocyte progenitor aggregation.