Hydrogel with ROS Scavenging Effect Encapsulates BR@Zn-BTB Nanoparticles for Accelerating Diabetic Mice Wound Healing via Multimodal Therapy

A zinc-based nanoscale metal−organic framework functioned as a carrier to deliver natural product berberine (BR) to form BR@Zn-BTB nanoparticles, which was further encapsulated by hydrogel with reactive oxygen species (ROS) scavenging ability to yield a composite system of BR@Zn-BTB/Gel (BZ-Gel).