NewslettersHuman Immunology NewsMethionine Consumption by Cancer Cells Drives a Progressive Upregulation of PD-1 Expression in CD4 T CellsBy Laurisa Dohm - May 9, 20230337Investigators developed nutrient-deprived media and a conditional knockout female mouse model to study the mechanism underlying PD-1 upregulation. Reduced methionine increased PD-1 expression on CD4 T cells.[Nature Communications]Full Article