Skin Basal Cell Carcinomas Assemble a Pro-Tumorigenic Spatially Organized and Self-Propagating Trem2⁺ Myeloid Niche

Within the highly proliferative neighborhood, scientists found out that TREM2+ skin cancer-associated macrophages supported the proliferation of a distinct tumor epithelial population through an immunosuppression-independent manner via oncostatin-M/JAK-STAT3 signaling.