NewslettersESC & iPSC NewsDeletion of p66Shc Dysregulates ERK and STAT3 Activity in Embryonic Stem Cells, Enhancing Their Naïve-Like Self-Renewal in the Presence of LIFBy Bob - May 17, 20230164Researchers determined whether p66Shc could act as a negative regulator of extracellular signal regulated kinase (ERK) activity during embryonic development, antagonizing early lineage commitment.[Stem Cells and Development]Abstract