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e.g. organoids

BRCA1 Insufficiency Induces a Hypersialylated Acidic Tumor Microenvironment That Promotes Metastasis and Immunotherapy Resistance

Investigators identified a mechanism mediated by sialyltransferases that induced an acidic tumor permissive microenvironment in BRCA1-mutant and most BRCA1-low breast cancers.
[Cancer Research]
Abstract
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