Suicide Gene Therapy Using Allogeneic Adipose Tissue-Derived Mesenchymal Stem Cell Gene Delivery Vehicles in Recurrent Glioblastoma Multiforme: A First-in-Human, Dose-Escalation, Phase I Clinical Trial

Researchers showed that suicide gene therapy using allogeneic adipose tissue-derived mesenchymal stem cells carrying the herpes simplex virus-thymidine kinase gene was safe in patients with recurrent glioblastoma multiforme.