Endothelial CCRL2 Induced by Disturbed Flow Promotes Atherosclerosis via Chemerin-Dependent β2 Integrin Activation in Monocytes

0
99
By analyzing scRNA-seq data of the left carotid artery under d-flow and scRNA-seq datasets GSE131776 of ApoE-/- mice, researchers found that CCRL2 was upregulated in one subpopulation of endothelial cells in response to d-flow stimulation and atherosclerosis.
[Cardiovascular Research]
AbstractGraphical Abstract