Insulin-Like Growth Factor (IGF) and Hepatocyte Growth Factor (HGF) in Follicular Fluid Cooperatively Promote the Oncogenesis of High-Grade Serous Carcinoma from Fallopian Tube Epithelial Cells: Dissection of the Molecular Effects

By
Laurisa Dohm
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In a mouse xenograft co-injection model, investigators observed that ovulatory follicular fluid co-injection induced tumorigenesis of serous tubal intraepithelial carcinoma-mimicking cells, FE25.
[Molecular Carcinogenesis]
Abstract