Pharmacological Inhibition of Neuropeptide Y Receptors Y1 and Y5 Reduces Hypoxic Breast Cancer Migration, Proliferation, and Signaling

Researchers measured the effects of neuropeptide Y (NPY) 1R and NPY5R antagonists in normoxia and hypoxia on migration, proliferation, invasion, and signaling in 2D and 3D models of breast cancer cell lines MDA-MB-231 and MCF7.