Autocrine Proteinase-Activated Receptor (PAR) Signaling in PC3 Prostate Cancer Cells
Investigators examined the androgen independent human prostatic cancer cell line PC3 and find functional expression of proteinase-activated receptor 1 (PAR1) and PAR2 but not PAR4.
[Cell & Bioscience] Scientists demonstrated that CDK1 was correlated with prognosis and was highly expressed in pancreatic cancer tissue and gemcitabine-resistant cells
[Acta Biomaterialia] Researchers demonstrated that incorporating human pancreatic decellularized extracellular matrix within alginate microcapsules resulted in a significant increase in Glucose Stimulation Index and total insulin secreted by encapsulated human islets, compared to free islets and islets encapsulated in only alginate.
[Cancer Letters] In vivo and in vitro experiments revealed that FABP4 induced macrophage-related inflammation to promote pancreatic cancer cell migration, invasion, and metastasis under obese condition.