LIMP-2 Enhances Cancer Stem-Like Cell Properties by Promoting Autophagy-Induced GSK3β Degradation in Head and Neck Squamous Cell Carcinoma

The authors identified a candidate gene named LIMP-2 as a novel therapeutic target regulating head and neck squamous cell carcinoma progression and CSC properties. The high expression of LIMP-2 in HNSCC patients suggested a poor prognosis and potential immunotherapy resistance.