FC-Competent Multispecific PDL-1/TIGIT/LAG-3 Antibodies Potentiate Superior Anti-tumor T Cell Response

Scientists reported the development of a PDL1 × TIGIT bi-specific antibody (bsAb) GB265, a PDL1 × LAG3 bsAb GB266, and a PDL1 × TIGIT × LAG3 tri-specific antibody GB266T, all with intact Fc function.