Endothelial-Specific Loss of IKKβ Disrupts Pulmonary Endothelial Angiogenesis and Impairs Postnatal Lung Growth

Researchers created a mouse model allowing inducible deletion of the nuclear factor-kappa B activator, IKKβ, in endothelial cells and assessed the effect on lung structure, endothelial angiogenic function, and the lung transcriptome.