USP9X Deubiquitinates and Stabilizes CDC123 To Promote Breast Carcinogenesis through Regulating Cell Cycle

Scientists identified a deubiquitinase, ubiquitin-specific peptidase 9, X-linked (USP9X), that could physically interact with and deubiquitinate K48-linked ubiquitinated cell division cycle 123 (CDC123) at the K308 site.