Tnpo3 Controls Splicing of the Pre-mRNA Encoding the Canonical TCR α Chain of iNKT Cells

The block of innate natural killer T cells (iNKT) cell development in the absence of Tnpo3 could be overcome by transgenic provision of a rearranged Trav11-Traj18-Trac cDNA, indicating that Tnpo3 deficiency did not interfere with the development of iNKT cells per se.