Targeting Collagen Damage for Sustained In Situ Antimicrobial Activities

Scientists found that the dimeric antimicrobial peptide Feleucin-K3 (Flc) and a collagen hybridizing peptide conjugate design preserved the potent and broad-spectrum antimicrobial activities of Flc, while significantly enhancing and extending its antimicrobial efficacy in vivo and facilitating tissue repair in a rat wound healing model.