A Novel Computational Method Enables RNA Editome Profiling During Human Hematopoiesis from scRNA-Seq Data

Scientists developed a computational method to systematically identify RNA editing sites of cell types from scRNA-seq data. It was applied to scRNA-seq data of human hematopoietic stem/progenitor cells with an annotated lineage differentiation relationship according to previous research and studied for the impacts of RNA editing on hematopoiesis.