MiR-494-3p Aggravates Pirarubicin-Induced Cardiomyocyte Injury by Regulating MDM4/p53 Signaling Pathway

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The effects of miR-494-3p on HL-1 contained in pirarubicin (THP) were investigated by CCK8, flow cytometry, ROS detection, JC-1 mitochondrial membrane potential detection, TUNEL cell apoptosis detection, RT-qPCR, and Western blot.
[Environmental Toxicology]
Abstract