Neferine Protected Cardiomyocytes against Hypoxia/Oxygenation Injury through SIRT1/Nrf2/HO-1 Signaling

A hypoxia/reoxygenation model with H9c2 cells closely simulating myocardia ischemia/reperfusion injury was used as a cellular model. Scientists investigated the effects and mechanism underlying neferine on H9c2 cells in response to ischemia/reperfusion stimulation.