Nootkatone Attenuates Airway Inflammation in Asthmatic Mice Through Repressing ROS-Induced NLRP3 Inflammasome Activation

Mice were sensitized and challenged with ovalbumin to establish an experimental allergic asthma model. After treatment with Nootkarone, lung tissues, peripheral blood, and bronchoalveolar lavage fluid were collected to assess inflammatory cytokines, oxidative stress, and pathological alternations.