ARHGAP4 Promotes Leukemogenesis in Acute Myeloid Leukemia by Inhibiting DRAM1 Signaling

Investigators studied lymphoma/leukemia-related activity in the evolving landscape of cells’ commitment to the erythroid lineage and specifically during fetal to adult hemoglobin transversion, to qualify transcription factors affecting chromatin remodeling as potential repressors of lncRNAs and miRNAs.