Harnessing Knee Joint Resident Mesenchymal Stem Cells in Cartilage Tissue Engineering

Scientists discuss the use of tissue engineering in osteoarthritis treatment and introduce the concept of a new generation of stem cell-based tissue engineering therapy, including the use of engineering, gene therapy, and gene editing techniques to create knee joint-derived (KJD)-MSCs or KJD-MSC derivative exosomes with improved functionality and targeted delivery.