CRISPR/Cas9-Mediated Inactivation of miR-34a and miR-34b/C in HCT116 Colorectal Cancer Cells: Comprehensive Characterization After Exposure to 5-FU Reveals EMT and Autophagy as Key Processes Regulated by miR-34

By
Jamie Kang
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0
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Researchers sought to determine their functional relevance by inactivating miR-34a and/or miR-34b/c using a CRISPR/Cas9 approach in the colorectal cancer cell line HCT116.
[Cell Death & Differentiation]
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