Black Phosphorus as a Targeting PPAR-γ Agonist to Reverse Chemoresistance in Patient-Derived Organoids, Mice, and Pancreatic Tumor Cells

Researchers investigated the potential of black phosphorous as a targeting PPAR-γ agonist to overcome chemoresistance in the treatment of pancreatic adenocarcinoma using 2D and 3D cell lines, patient-derived organoids, and mouse models.