Microfluidic Intestinal Organoid-on-a-Chip Uncovers Therapeutic Targets by Recapitulating Oxygen Dynamics of Intestinal IR Injury

Inspired from the structure of native intestinal villi, scientists engineered an intestinal organoid chip embedded with engineered artificial microvessels based on co-axial microfluidic technology by using pH-responsive ZIF-8/sodium alginate scaffold.