Entry Receptor LDLRAD3 Is Required for Venezuelan Equine Encephalitis Virus Peripheral Infection and Neurotropism Leading to Pathogenesis in Mice

Using wild-type and Ldlrad3-deficient mice, scientists defined a critical role for low-density lipoprotein receptor class A domain-containing 3 (LDLRAD3) in controlling steps in venezuelan equine encephalitis virus infection, pathogenesis, and neurotropism.