Cardiomyocyte Proliferation Is Suppressed by ARID1A-Mediated YAP Inhibition during Cardiac Maturation

Investigators showed that AT-rich interactive domain-containing protein 1a (Arid1a), a subunit of the switching defective/sucrose non-fermenting chromatin remodeling complex, suppressed postnatal cardiomyocyte proliferation while enhancing maturation.