Photothermal-Triggered Sulfur Oxide Gas Therapy Augments Type I Photodynamic Therapy for Potentiating Cancer Stem Cell Ablation and Inhibiting Radioresistant Tumor Recurrence

A near-infrared laser-induced synergistic therapeutic platform had been developed by incorporating aggregation-induced emission-active phototheranostic agents and sulfur dioxide prodrug into a biocompatible hydrogel to suppress malignant CSC growth.