Coalescent RNA-Localizing and Transcriptional Activities of SAM68 Modulate Adhesion and Subendothelial Basement Membrane Assembly

The authors found that SAM68 was transiently localized at the edge of spreading cells where it participates in membrane protrusive activity and the conversion of nascent adhesions to mechanically loaded focal adhesions by modulation of integrin signaling and local delivery of β-actin mRNA.