Topical Application of TOPK Inhibitor OTS514 Suppresses Psoriatic Progression by Inducing Keratinocytes Cell Cycle Arrest and Apoptosis

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Researchers aimed to investigate the expression and role of T-LAK cell-oriented protein kinase (TOPK) in psoriasis, and the role of TOPK inhibitor in psoriasis attenuation.
[Experimental Dermatology]
Abstract