NewslettersEndothelial Cell NewsRepression of rRNA Gene Transcription by Endothelial SPEN Deficiency Normalizes Tumor Vasculature via Nucleolar StressBy Laurisa Dohm - August 28, 20230142Scientists showed that split end (SPEN), a transcription repressor, coordinated ribosome RNA synthesis in endothelial cells and was required for physiological and tumor angiogenesis.[Journal Of Clinical Investigation]AbstractFull ArticleGraphical Abstract