miR-126 Identifies a Quiescent and Chemo-Resistant Human B-ALL Cell Subset That Correlates with Minimal Residual Disease

Investigators exploited patient-derived xenograft models with B cell acute lymphoblastic leukemia (B-ALL) cells transduced with a miR-126 reporter allowing the prospective isolation of miR-126(high) cells for their functional and transcriptional characterization.