Enhanced Drug Loading Capacity of Graphene Oxide Nanoparticles by Polyglycerol Hyper Branching and Increasing the Sensitivity of Osteosarcoma Cancer Cells to Doxorubicin

Doxorubicin electrochemically linked to the surface of pH-sensitive polyhydroxy glycerol-grafted graphene oxide nanoparticles, and its loading capacity, release efficiency, and cytotoxicity was assessed using various molecular tests such as flow cytometry, RT-PCR, MTT, and apoptosis assay.