Human Umbilical Cord Derived Mesenchymal Stem Cells Overexpressing HO-1 Attenuate Neural Injury and Enhance Functional Recovery by Inhibiting Inflammation in Stroke Mice

The middle cerebral artery occlusion mouse model was established, and subsequent injections of MSC, MSCheme oxygenase-1 (HO-1), or PBS solutions of equal volume were administered via the mice’s tail vein.