Aerosol Delivery of a Novel Recombinant Modified Superoxide Dismutase Protein Reduces Oxidant Injury and Attenuates Escherichia coli Induced Lung Injury in Rats

Researchers investigated the therapeutic potential of a novel recombinant human Cu-Zn-superoxide dismutase (SOD) fusion protein in protecting against reactive oxygen species injury and for aerosolized SOD delivery to treat Escherichia coli induced acute respiratory distress syndrome.