m6A-Modified miR-143-3p Inhibits Epithelial Mesenchymal Transition in Bronchial Epithelial Cells and Extracellular Matrix Production in Lung Fibroblasts by Targeting Smad3

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MiR-143-3p inhibited airway epithelial cell epithelial mesenchymal transition as well as lung fibroblast extracellular matrix production by downregulating Smad3. Therefore, miR-143-3p may be a promising target to reduce airway remodeling in asthma.
[Pulmonary Pharmacology & Therapeutics]
AbstractGraphical Abstract