The Functional Maturity of Grafted Human Pluripotent Stem Cell Derived-Islets (hSC-Islets) Evaluated by the Glycemic Set Point During Blood Glucose Normalizing Process in Diabetic Mice

Scientists utilized two kinds of streptozotocin-induced diabetes model mice by changing the administration timing in order to examine the time course of maturation of hSC-islets and the effects of hyperglycemia on their maturation.