The Inhibition of Pancreatic Cancer Progression by K-Ras-Overexpressing Mesenchymal Stem Cell-Derived Secretomes

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Overexpression of K-Ras elevated PI3K signaling in MSCs, and K-Ras/PI3K-activated MSC-derived CM reduced the proliferation and migration of tumor cells, as well as the growth of ex vivo freshly isolated human PDAC cultures.
[Scientific Reports]
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