Subscribe
e.g. organoids

Breaking through the Basement Membrane Barrier to Improve Nanotherapeutic Delivery to Tumours

Scientists demonstrated that, in addition to the endothelial barrier, the tumor vascular basement membrane surrounding the endothelium acted as a formidable mechanical barrier that entrapped nanoparticles in the subendothelial void.
[Nature Nanotechnology]
Abstract
Published In
NewslettersEndothelial Cell News
spot_img

Stay up-to-date with your field!

Subscribe for free weekly science newsletters.

Related News

Regulatory T Cells Require IL6 Receptor Alpha Signaling to Control Skeletal Muscle Function and Regeneration

[Cell Metabolism] Using exercise and sarcopenia models, mice lacking IL6Rα on T cells demonstrated deficits in regulatory T cells, their functional maturation, and a more pronounced decline in muscle mass.
Immune Regulation NewsMuscle Cell NewsNewsletters
Read more

Oncometabolite D-2-Hydroxyglutarate—Dependent Metabolic Reprogramming Induces Skeletal Muscle Atrophy during Cancer Cachexia

[Communications Biology] Based on the up-regulation of catabolism and down-regulation of anabolism, researchers showed genetic mutation-mediated metabolic reprogramming in the progression of cancer cachexia by screening for metabolites and investigating their direct effect on muscle atrophy.
Muscle Cell NewsNewsletters
Read more

Myeloid-Derived Growth Factor Suppresses VSMC Dedifferentiation and Attenuates Postinjury Neointimal Formation in Rats by Activating S1PR2 and Its Downstream Signaling

[Acta Pharmacologica Sinica] Researchers investigated the effect of myeloid-derived growth factor to postinjury neointimal formation and the underlying mechanisms. Rat carotid arteries balloon-injured model was established.
Muscle Cell NewsNewsletters
Read more
Brought to you by