Activation of Vascular Endothelial Cells by Synovial Fibrosis Promotes Netrin-1-Induced Sensory Nerve Sprouting and Exacerbates Pain Sensitivity

Investigators established a co-culture model of (HUVECs with dorsal root ganglion to investigate the intervention of vascular endothelial cell activation on sensory nerve sprouting exacerbating peripheral pain sensitivity.