NewslettersHuman Immunology NewsMetabolic Reprogramming via ACOD1 Depletion Enhances Function of Human Induced Pluripotent Stem Cell-Derived CAR-Macrophages in Solid TumorsBy Bob - September 19, 20230365Scientists found, via a pooled metabolic gene knockout CRISPR screen that KEAP1 and ACOD1 were strong regulators of the pro-inflammatory state in macrophages.[Nature Communications]Full Article