Clinical Significance of Porphyromonas gingivalis Enriching Cancer Stem Cells by Inhibiting Programmed Cell Death Factor 4 in Esophageal Squamous Cell Carcinoma

Scientists investigated the functional mechanism by which Porphyromonas gingivalis (Pg) promoted esophageal squamous cell carcinoma (ESCC) chemoresistance and malignancy through inhibiting PDCD4 and enriching CSCs. The effects of Pg and programmed cell death factor 4 on CSCs, chemoresistance, and malignancy of ESCC cells were evaluated by in vitro studies.