TAZ Facilitates Breast Tumor Growth by Promoting an Immune-Suppressive Tumor Microenvironment

To elaborate the roles of TAZ in TNBC, the authors depleted Taz in murine TNBC 4T1 cells, using either CRISPR/Cas9 or small hairpin RNA. TAZ depletion resulted in smaller tumors compared to the tumors generated by control cells.