The Role of LOXL2 Induced by Glucose Metabolism-Activated NF-κB in Maintaining Drug Resistance through EMT and Cancer Stemness in Gemcitabine-Resistant PDAC

Researchers investigated the mechanism of lysyl oxide-like 2 (LOXL2) induction and the effect of LOXL2 on epithelial to mesenchymal transition (EMT) and CSC in gemcitabine-resistant pancreatic cancer.