NewslettersPulmonary Cell NewsYAP Silencing by RB1 Mutation Is Essential for Small-Cell Lung Cancer MetastasisBy Jamie Kang - September 28, 20230238Researchers found that loss of YAP expression is key for SCLC cells to acquire rapid ameboid migration and high metastatic potential. YAP functions through its target genes CCN1/CCN2 to inhibit SCLC ameboid migration.[Nature Communications]Full Article