Differential Roles of Highly Expressed PFKFB4 in Colon Adenocarcinoma Patients

Researchers investigated the clinical significance of PFKFB4 in colon adenocarcinoma (COAD) by studying its expression in 79 tissue samples using immunohistochemistry. They found that PFKFB4 expression was significantly higher in COAD patients, particularly in the sigmoid colon.