Human Umbilical Cord Mesenchymal Stem Cells Ameliorate Colon Inflammation via Modulation of Gut Microbiota-SCFAs-Immune Axis

Researchers investigated for the first time the role of gut microbiota in mediating the protective effect of human umbilical cord MSCs on 2% dextran sodium sulfate-induced colitis. Gut microbiota alteration and short-chain fatty acids production were analyzed through 16S rRNA sequencing and targeted metabolomics.