Polyphyllin I Induces Ferroptosis in Castration-Resistant Prostate Cancer Cells through the ERK/DNMT1/ACSL4 Axis

Polyphyllin I (PPI), one of the steroidal saponins in paris polyphylla, has been shown to have an anticancer effect. Researchers investigated the role and mechanism of PPI in CRPC cell ferroptosis.